Tuesday, January 4, 2022

The Cameroon Mutation - Is This the Next COVID-19 Vaccine Escapee?

With the COVID-19 vaccines showing a lack of efficacy against the latest SARS-CoV-2 mutation, recent research from France gives us a sense of what lies ahead no matter what mechanisms governments put in place to control the spread of the virus.

 

Scientists in Marseilles, France have released this preprint (not peer reviewed) entitled "Mergence in Southenr France of a new SARS-CoV-2 variant of probably Cameroonian origin harbouring both substitutions N501Y and E484K in the spike protein:

 


The research was funded by the French government under the "Investments for the Future" program managed by the National Agency for Research among other supporters.

 

In the paper, the researchers note that SARS-CoV-2 variants have become a major concern since they are able to escape from vaccine-induced immunity.  The index case of yet another variant returned from travel in Cameroon three days prior to testing and, after exhibiting mild respiratory symptoms, underwent a private RT-PCR test from a sample collected in mid-November 2021, the day after symptoms appeared.  It is important to note that the subject was vaccinated against SARS-CoV-2.  The test revealed an atypical combination of mutations in the spike gene which did not correspond to the pattern of the Delta variant which was involved in nearly all of the SARS-CoV-2 infections at that time.

 

The researchers also collected samples from two adults and five children living in the same geographical area who tested positive for SARS-CoV-2.  The samples from all seven of these infected individuals exhibited the same combination of mutations that were seen in the traveller who had returned from Cameroon.

 

Samples from all eight individuals were sent to the University Hospital Institute (IHU) Mediterranee Infection for genome sequencing.  The analysis of viral genomes revealed the presence of 46 nucleotide substitutions and 37 deletions resulting in 30 amino acid substitutions and 12 selections with 14 amino acid substitutions and 9 amino acid deletions being located in the spike protein.  This suggests that a new variant has evolved which the researchers termed "IHU", in reference to the name of their institute of study. 

  

Respiratory samples collected until the end of November 2021 from four additional SARS-CoV-2 positive patients living in the same city or borough as the index case were also shown to contain the IHU variant, showing the same combination of spike mutations.

 

Here is the rather stunning conclusion of the study:

 

"Overall, these observations show once again the unpredictability of the emergence of new SARS-CoV-2 variants and their introduction from abroad, and they exemplify the difficulty to control such introduction and subsequent spread."


Interestingly, Dr. Geert Vanden Bossche has repeatedly warned about the escape of new variants, thanks to the implementation of vaccines during this pandemic.  Here is one of many videos showing his impressive credentials and his thoughts on viral escape if you are interested in more details on the science of viral evolution.

 

How long will it be before governments realize that they are trying to "stuff the genie back into the bottle" by mandating ever increasing numbers of booster shots?  The SARS-CoV-2 virus is proving that it will continue to mutate to new forms which are capable of evading the experimental vaccines which are clearly less than effective at preventing the spread of the virus no matter what proportion of human beings are vaccinated.


4 comments:

  1. But why would anyone be surprised by this. It is from the same family of viruses as the flu and vaccines are really hit and miss with that. Of course the difference is there are no widespread mandates for the flu vaccine..

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  2. I suggest we should be planning [predicting ahead] on how things could possibly progress [TPTB certainly do forward planning and reactive advantage optimization -proactive and reactive] so here are some 'avenues' that may be walked down in the near future:
    They mandate forcible vaccination and end up 95+ % fully vaccinated in country x.... but as not all the entire planet is 'fully vaccinated', the focus is now on international travelers as the not fully vaccinated countries are spawning new variants and these are 'somehow' entering country x, the international travelers are blamed so compulsory quarantining and testing goes on until the entire traveled world is fully vaccinated. ( or international freight is blamed for transmission so all such freight subjected to expensive testing and delay/ supply chain scenario /inflation/ empty shelves etc)- air fares could rocket accordingly in either scenario.
    OR, country x is fully vaccinated AND isolated, but still the virus is infecting people, making some ill, some seriously and some dying so now "the pandemic of the vaccinated" won't wash and the "fully vaccinated" now demonise not sufficiently up to date fellow vacinees and now call it "the pandemic of the 'not-fully vaccinated' and force by Law their current booster level deemed necessary on the 'insufficiently vaccinated'.
    OR, and as it has been scientifically claimed, they know sperm can harbour the virus ( as can urine,vomit, spit,tears,blood,excreta, breast milk) so before you can have a male penis entering any orifice of another human they must be proven to be virus free.... licking stamps, French kissing, mothers breast feeding,Public urinals or family toilet pans,blood transfusions could all become problematic... and cash cows .
    OR, domestic pets or internal borders fodder animals get blamed, tested,vaccinated?, slaughtered-but-not-suitable for consumption?
    Right now in the UK we have a daily increasing societal rift with "the vaccinated are occupying/monopolizing valuable hospital beds and killing vaccinated people who need treatment", with many saying the UK should do as Singapore has: no vaccination and you pay the full medical costs... the National Health Service NHS becoming the Vaccine Health Service VHS ? ... we are not living in interesting times more apt, very dangerous times.

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  3. * Corresponding author:
    Didier Raoult, IHU Méditerranée Infection,


    This is the same dubious character who gave us the miracle drug "hydroxychloroquine" in a paper that was so bad that it has led to him being investigated for ethical violations
    Le Dr Didier Raoult blâmé par l’Ordre des médecins de France

    I would take any conclusions from this paper with a grain of salt.

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  4. @ KILLERFLUFFY January 4, 2022 at 5:43 PM
    I have no confidence in the paper but from what little I know of coronaviruses I must agree. No surprise.

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